Gynocare (Metronidazole + Neomycin + Polymixin B + Nystatin)

Gynocare is a combination medication used for the treatment of various vaginal infections. It contains four active ingredients: Metronidazole, Neomycin, Polymyxin B, and Nystatin. Here's an overview of each component:

Metronidazole

• Type: Antibiotic (Nitroimidazole)
• Mechanism of Action: Disrupts the DNA structure of bacteria and some parasites, leading to their death or inhibition of growth.
• Uses: Effective against anaerobic bacteria and certain parasites. It is commonly used to treat bacterial vaginosis, trichomoniasis, and other bacterial infections.

Neomycin

• Type: Antibiotic (Aminoglycoside)
• Mechanism of Action: Inhibits bacterial protein synthesis, leading to bacterial cell death.
• Uses: Effective against a wide range of bacteria. It is often used to prevent or treat bacterial infections in wounds, burns, and skin conditions.

Polymyxin B

• Type: Antibiotic (Polypeptide)
• Mechanism of Action: Disrupts the bacterial cell membrane, causing leakage of cellular contents and cell death.
• Uses: Effective against Gram-negative bacteria, including some strains that are resistant to other antibiotics.

Nystatin

• Type: Antifungal (Polyene)
• Mechanism of Action: Binds to ergosterol in fungal cell membranes, disrupting membrane integrity and leading to fungal cell death.
• Uses: Effective against a wide range of fungi, including Candida species. It is commonly used to treat fungal infections, including vaginal yeast infections.

Uses

• Vaginal Infections: Gynocare is used to treat bacterial vaginosis, trichomoniasis, yeast infections (vaginal candidiasis), and other vaginal infections caused by bacteria or fungi.